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A Grandmother’s Smoking Can Affect Grandchildren’s Asthma Risk

Childhood asthma risk is affected not only by mother’s smoking, but by in utero exposure to grandmother’s smoking. A recent longitudinal study was performed to evaluate effects of grandmother’s smoking on childhood asthma risk. It looked at 966 cases of asthma and 5,915 controls without asthma.

Prenatal exposure of the mother to cigarette smoke did not affect the grandchildren’s risk of being diagnosed with asthma. However, paternal prenatal exposure to their own mother’s smoking was associated with increased risk of persistent wheezing in the daughters of those fathers.

While these results are interesting, the author caution that the results are based on reported symptoms without corroborating biologic evidence.

Saraleen Benouni, MD Dr. Benouni specializes in the treatment of asthma, allergies, atopic dermatitis, and immune disorders for both adults and children. She has presented and published research at national allergy meetings and has authored papers on drug allergies and skin conditions. She is a member of the American College and American Academy of Allergy, Asthma, and Immunology, and the Los Angeles Society of Allergy, Asthma, and Clinical Immunology.

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