Two large trials, DREAM and MENSA have found IL-5 therapy with mepolizumab to lower risk of exacerbation in patients with asthma with an eosinophilic phenotype.
There is lack of evidence to describe any dog breed as hypoallergenic. A recent article sampled dog hair and coat, settled floor dust, and airborne samples. It demonstrated that hypoallergenic dogs such as labradoodle, poodle, Spanish waterdog, and Airedale terrier, are no less allergenic than any other dogs. Can f 1 (dog allergen protein) levels are significantly high in hair and coat samples of “hypoallergenic dogs”. A similar study in July 2011, demonstrated that dog allergen levels in homes of hypoallergenic versus nonhypoallergenic dogs had no significant difference.
High levels of Can f 1 are found in settled dust in carpets, upholstered furnishings, pillows and blankets in homes. Can f 1 is present in classrooms, airplanes, automobiles, hospitals and even households without dogs.
The main cat allergen, Fel d 1 is also widely dispersed in indoor environments. As the prevalence of household pets has increased, so has the incidence of allergic disease.
Pet owners should train their pets to stay out of bedrooms and beds. The most allergen exposure is while sleeping. Patients with dog or cat allergy should avoid getting pets as there is no such animal as a hypoallergenic dog or cat.
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Two large trials, DREAM and MENSA have found IL-5 therapy with mepolizumab to lower risk of exacerbation in patients with asthma with an eosinophilic phenotype.
Mold allergy is difficult to diagnose due to lack of standardized test material.
The current standard for diagnosis of Eosinophilic Esophagitis (EoE) is endoscopy with esophageal biopsy to determine the eosinophil count
Skin prick testing and serum IgE measurement are limited in their ability to predict positive or negative responses to oral peanut challenge.
Bronchial Thermoplasty (BT) has been shown to result in significant improvements in a number of asthma control measures in three randomized clinical trials in patients with moderate-to-severe, persistent asthma.
Recent studies have suggested that early regular exposure to allergenic foods may reduce the risk of food allergy.